🛠️Machine Learning Engineer - Agentic AI for Claim Denials
Joyful Health
Software Engineering, Data Science
Posted on Nov 27, 2025
Machine Learning Engineer - Agentic AI for Claim Denials
About Joyful Health
Building the financial operating system for healthcare, and bringing the joy back to healthcare by fixing the financial chaos behind it.
The healthcare payment system is a complex and inefficient maze - healthcare practices leave $125 billion in revenue uncollected each year, lost in the chaos of fragmented financial data, manual workflows, and opaque payer systems. This financial uncertainty leaves practices struggling to stay afloat, while valuable revenue slips through the cracks.
Joyful Health is building the AI-powered financial operating system for healthcare practices. Our mission is to bring the joy back to running a private practice by simplifying financial operations so providers can focus on patient care. We spent 10 months working as fractional CFOs for a dozen practices, doing this work side by side with providers as we developed our product.
We just closed a funding round led by world-class investors and angels including the founders of MongoDB & KAYAK.
We have an enormous opportunity in front of us. The broken healthcare payment ecosystem impacts practices of all sizes, and the opportunity to make a real difference is massive. If you’re passionate about empowering medical practices and excited to tackle one of the most important (& challenging!) problems in healthcare, we’d love to meet you. Apply here: Joyful Health CareersJoyful Health Careers​
The Role
Role Description
We're looking for a talented and ambitious machine learning engineer with 5+ years of experience building production AI systems who's excited to solve one of the toughest challenges in healthcare - automatically resolving claim denials. You'll be the technical lead for our agentic AI platform that autonomously researches, understands, and resolves insurance claim denials, helping healthcare practices recover millions in lost revenue.
Insurance claim denials cost healthcare practices $125 billion annually, and resolving them requires deep expertise in medical billing, payer rules, and claim documentation. Today, billing managers spend hours manually researching each denial, gathering supporting documentation, and crafting appeals. We're building an agentic AI system that automates this entire workflow - from denial classification and root cause analysis, to evidence gathering and appeal letter generation.
As a machine learning engineer, you'll architect and build the intelligent agents that power this system. You'll design multi-agent workflows that collaborate to interpret complex denial reasons, retrieve relevant clinical and billing information through RAG systems, reason about payer policies, and generate compelling appeals. This is a greenfield opportunity to build a production agentic system that will directly impact the financial health of healthcare practices.
You should be comfortable (and excited!) about working in a fast-paced, early-stage startup environment where you'll be able to wear many hats and take on new challenges as they arise. This is a great opportunity for someone who wants to work on something extremely challenging at the intersection of AI and healthcare.
This role is full-time. We're looking for candidates based in NYC.
What you'll do
Design and build the architecture for our agentic AI system that autonomously resolves insurance claim denials
Develop specialized AI agents for denial classification, root cause analysis, evidence retrieval, policy reasoning, and appeal generation
Implement multi-agent orchestration frameworks that coordinate complex workflows across research, decision-making, and document generation
Build and optimize RAG systems to retrieve relevant clinical documentation, billing records, and payer policy information
Create evaluation frameworks and feedback loops to continuously improve agent performance and reliability
Design prompt engineering strategies and fine-tuning approaches to optimize LLM behavior for healthcare billing workflows
Work closely with billing managers to understand denial resolution workflows and translate them into agent behaviors
Collaborate with the engineering team on production infrastructure for deploying and monitoring AI agents at scale
Actively contribute to building the team's AI/ML vision and technical roadmap
Collaborate on code reviews and technical design documents to ensure code quality and distribute knowledge
We’d love to hear from you if…
You’re passionate about Joyful Health’s mission – you want to solve real, pressing problems for providers and put them in control of their businesses. You naturally empathize with users and enjoy designing solutions with their needs in mind.
You’re excited to shape the future of our engineering team and are excited to lead by example – as an early team member, you’ll have the chance to influence everything from our technical roadmap to our company culture. You have a radical sense of ownership with the ability and desire to own technical roadmaps and refine ambiguous problems. You also have a low ego, growth mindset, and desire to see the product and team scale with your impact.
You have a love for your craft and strong technical execution - you view coding as a craft, not just a task, and you're excited about using technology to create meaningful impact. Your technical skills go beyond coding—you care about building a product that works at scale, with the user at the forefront. We care more about your drive, hustle, and passion than a college degree from a shiny institution or experience at name-brand companies.
You have 5+ years of experience in machine learning engineering, with a focus on building production AI systems and deploying models at scale.
Strong experience with machine learning frameworks (PyTorch, TensorFlow, or JAX)
Experience working with healthcare data or understanding of medical billing workflows is a plus
Proficiency in:
Python and modern ML frameworks (PyTorch, TensorFlow, or JAX)
LLM technologies including prompt engineering, fine-tuning, and RAG systems
Vector databases and semantic search systems
Building reliable, production-grade AI systems with proper evaluation and monitoring
MLOps practices including model versioning, A/B testing, and performance tracking
Working with APIs and integrating AI systems into broader product workflows
Our Value Prop to You
At Joyful Health, we’re on a mission to fix one of the most broken systems in healthcare. Joining us means having the opportunity to make a direct, meaningful impact on the lives of clinicians and the financial health of their practices. Here’s what you can expect from working with us:
Meaningful Impact You’ll be tackling one of the most complex challenges in healthcare—helping practices thrive in a chaotic financial landscape. Your work will directly contribute to solving one of the most hair on fire problems for providers, ensuring that they can focus on what they do best: caring for patients.
Autonomy & Ownership As an early team member, you’ll have significant autonomy and the chance to shape our company from the ground up. You’ll have ownership over your work and the freedom to challenge the status quo in an environment that values initiative and creativity.
Growth & Learning We’re a small, ambitious team with big goals, which means you’ll be constantly learning and growing. You’ll take on new challenges, expand your skill set, and have direct access to experienced founders and advisors who are invested in your development. We also offer stipends for professional development courses & books (that we often will partake in together!) so we can all continuously grow.
Competitive Compensation & Equity We believe that our team is our most valuable asset. We offer competitive compensation packages, strong equity, and the opportunity to share in the success of Joyful Health. We want you to feel supported, both financially and professionally, as we grow together.
Be Your Best Self We provide the benefits you need to stay happy and healthy, including comprehensive healthcare benefits, unlimited PTO (with a minimum of 10 days off a year), and flexibility so you can take care of yourself. We also organize regular team off-sites and events to ensure that even as we tackle big problems we enjoy the journey.
If you’re passionate about empowering practices and excited to tackle one of the most important (& challenging!) problems in healthcare, we’d love to meet you. Please apply even if you don't meet 100% of the criteria. Nobody checks every box every time and we'd love to talk to you about how and why you can see yourself growing into this role. We're also very open to candidates with non-traditional experience. Apply here: Joyful Health CareersJoyful Health Careers​